Some heart disease risk factors, such as genetics, cannot be controlled. However, many other heart disease risk factors can be modified. Eating heart-healthy foods can reduce the risk of heart disease. Heart-healthy foods include fruits, and vegetables. Cholesterol-lowering foods such as beans, soy, chickpeas, garlic, avocados, and olive oil are beneficial. Boost levels of HDL "good" cholesterol by eating nuts. Walnuts, pecans, and almonds are good choices, but limit your serving to a small handful as nuts are high in calories. It's a good idea to eat fish and seafood a few times a week to boost intake of heart-healthy omega-3 fatty acids . Avoid sugary foods as they promote heart disease and other chronic conditions.
Since the 1990s the search for new treatment options for coronary artery disease patients, particularly for so called "no-option" coronary patients, focused on usage of angiogenesis  and (adult) stem cell therapies. Numerous clinical trials were performed, either applying protein (angiogenic growth factor ) therapies, such as FGF-1 or VEGF , or cell therapies using different kinds of adult stem cell populations. Research is still going on – with first promising results particularly for FGF-1   and utilization of endothelial progenitor cells .