Their common thread? They did not allow nicotine back into their bloodstream. Quitting is all or nothing. It's called the Law of Addiction . Nicotine dependence is real drug addiction. It's as permanent as alcoholism. The wanting and urges you feel for more nicotine flow from the same brain dopamine pathways as the wanting felt by the alcoholic, and the heroin, cocaine and methamphetamine addict. As suggested by the Law , there is only one rule to successful quitting. It's that one equals all, that we cannot cheat the design of dopamine pathways already compromised by nicotine. For us, one puff will always be too many, while thousands never enough.